abstract：BACKGROUND:Several compounds isolated from Dryobalanops have been reported to exhibit cytotoxic effects to several cancer cell lines. This study investigated the cytotoxic effects, cell cycle arrest and mode of cell death in ampelopsin E-treated triple negative cells, MDA-MB-231. METHODS:Cytotoxicity of ampelopsin E, ...

journal_title：BMC complementary and alternative medicine

authors： Rahman NA,Yazan LS,Wibowo A,Ahmat N,Foo JB,Tor YS,Yeap SK,Razali ZA,Ong YS,Fakurazi S

更新日期：2016-09-08 00:00:00

abstract：BACKGROUND:Sanguisorbae Radix (SR) is a well-known herbal medicine used to treat inflammatory disease and skin burns in Asia. In addition, it is used to treat many types of allergic skin diseases, including urticaria, eczema, and allergic dermatitis. SR has been reported to exhibit anti-wrinkle, anti-oxidant, and anti-...

journal_title：BMC complementary and alternative medicine

authors： Yang JH,Yoo JM,Cho WK,Ma JY

更新日期：2016-09-06 00:00:00

abstract：BACKGROUND:Psoriasis is a chronic inflammatory immune disease with undefined pathogenesis. It is associated with T cells, and the IL-23/IL17 axis is believed to be crucial in the pathogenesis. The present treatments have side effects that influence the compliance of patients. Tea polyphenol is extracted from tea polyph...

journal_title：BMC complementary and alternative medicine

authors： Zhang S,Liu X,Mei L,Wang H,Fang F

更新日期：2016-08-31 00:00:00

abstract：BACKGROUND:Periodontitis has been implicated as a risk factor for metabolic disorders associated with insulin resistance. Recently, we have demonstrated that orally administered Porphyromonas gingivalis, a representative periodontopathic bacterium, induces endotoxemia via reduced gut barrier function coupled with chang...

journal_title：BMC complementary and alternative medicine

authors： Nakajima M,Arimatsu K,Minagawa T,Matsuda Y,Sato K,Takahashi N,Nakajima T,Yamazaki K

更新日期：2016-08-30 00:00:00

abstract：BACKGROUND:Protein tyrosine phosphatase expressed in insulin-sensitive tissues (such as liver, muscle, and adipose tissue) has a key role in the regulation of insulin signaling and pathway activation, making protein tyrosine phosphatase a promising target for the treatment of type 2 diabetes mellitus and obesity and re...

journal_title：BMC complementary and alternative medicine

authors： Hwang SH,Kwon SH,Wang Z,Kim TH,Kang YH,Lee JY,Lim SS

更新日期：2016-08-26 00:00:00

abstract：BACKGROUND:Traditional fermented cheese whey (TFCW), containing probiotics, has been used both as a dairy food with ethnic flavor and a medicine for cardiovascular disease, especially regulating blood lipid among Kazakh. We therefore investigated anti-atherosclerotic effects of TFCW in atherosclerotic rabbits and ident...

journal_title：BMC complementary and alternative medicine

authors： Nabi XH,Ma CY,Manaer T,Heizati M,Wulazibieke B,Aierken L

更新日期：2016-08-24 00:00:00

abstract：BACKGROUND:Catharanthus roseus, a medicinal plant, is known to produce secondary metabolites, vincristine and vinblastine, which are terpenoid indole alkaloids. Previously we have reported that Eutypella spp - CrP14 isolated from stem cutting of this plant had shown significant antiproliferative activity when tested in...

journal_title：BMC complementary and alternative medicine

authors： Kuriakose GC,Palem PP,Jayabaskaran C

更新日期：2016-08-22 00:00:00

abstract：BACKGROUND:Diabetes is a growing burden in sub-Saharan Africa where traditional medicines (TMs) remain a primary form of healthcare in many settings. In Tanzania, TMs are frequently used to treat non-communicable diseases, yet little is known about TM practices for non-communicable diseases like diabetes. METHODS:Betw...

journal_title：BMC complementary and alternative medicine

authors： Lunyera J,Wang D,Maro V,Karia F,Boyd D,Omolo J,Patel UD,Stanifer JW,Comprehensive Kidney Disease Assessment For Risk factors, epidemiology, Knowledge, and Attitudes (CKD AFRiKA) Study.

更新日期：2016-08-11 00:00:00

abstract：BACKGROUND:Carrageenan is a sulfated polysaccharide that exists in red seaweeds recently shown to have anticancer properties. Previous findings show various effects of carrageenan suppressing tumor cell growth. One of the hallmarks of cancer is uncontrolled proliferation, a consequence of loss of normal cell-cycle cont...

journal_title：BMC complementary and alternative medicine

authors： Prasedya ES,Miyake M,Kobayashi D,Hazama A

更新日期：2016-08-04 00:00:00

abstract：BACKGROUND:The study aimed to evaluate the effects of Acacia honey (AH) on the migration, differentiation and healing properties of the cultured rabbit corneal fibroblasts. METHODS:Stromal derived corneal fibroblasts from New Zealand White rabbit (n = 6) were isolated and cultured until passage 1. In vitro corneal ulc...

journal_title：BMC complementary and alternative medicine

authors： Abd Ghafar N,Ker-Woon C,Hui CK,Mohd Yusof YA,Wan Ngah WZ

更新日期：2016-07-29 00:00:00

abstract：BACKGROUND:Psoriasis is a chronically recurrent inflammatory skin disease, modern medicine could achieve good therapeutic effect, but these treatments led to recurrence of the psoriasis, more severe symptoms due to damaging skin barrier. Traditional Chinese medicine is a useful alternative therapies. The purpose of thi...

journal_title：BMC complementary and alternative medicine

authors： Wei JA,Han L,Lu CJ,Zhao RZ,Sun J,Lu Y,Lin HJ

更新日期：2016-07-29 00:00:00

abstract：BACKGROUND:Pain, the most common reasons for physician consultation, is a major symptom in many medical conditions that can significantly interfere with a person's life quality and general functioning. Almost all painkillers have its untoward effects. Therefore, seeking for a safe medication for pain relieve is notable...

journal_title：BMC complementary and alternative medicine

authors： Chen YF,Lee MM,Fang HL,Yang JG,Chen YC,Tsai HY

更新日期：2016-07-26 00:00:00

abstract：BACKGROUND:Tangshen Formula (TSF) is a traditional Chinese medicine for the treatment of diabetic kidney disease (DKD). Liver-type fatty acid binding protein (L-FABP) is expressed in various tissues, including the kidney, where it is known as urinary L-FABP. Other studies demonstrated that urinary L-FABP may be a usefu...

journal_title：BMC complementary and alternative medicine

authors： Yang X,Zhang B,Lu X,Yan M,Wen Y,Zhao T,Li P

更新日期：2016-07-26 00:00:00

abstract：BACKGROUND:Liver steatosis was caused by lipid accumulation in the liver. Alisma orientale (AO) is recognized as a promising candidate with therapeutic efficacy for the treatment of nonalcoholic fatty liver disease (NAFLD). HepG2 hepatocyte cell line is commonly used for liver disease cell model. METHOD:The HepG2 cell...

journal_title：BMC complementary and alternative medicine

authors： Jeong HS,Cho YH,Kim KH,Kim Y,Kim KS,Na YC,Park J,Lee IS,Lee JH,Jang HJ

更新日期：2016-07-25 00:00:00

abstract：BACKGROUND:Plant medicinal extracts may be claimed to prevent or cure chemical intoxications. Few of these are tested for their mechanisms of actions in vivo and for their cellular impacts. In 2011, we demonstrated that hepatic cell mortality induced by environmentally realistic levels of the widely used herbicide Roun...

journal_title：BMC complementary and alternative medicine

authors： Gress S,Laurant C,Defarge N,Travert C,Séralini GÉ

更新日期：2016-07-22 00:00:00

abstract：BACKGROUND:Ayurveda is a system of traditional medicine that originated in ancient India, and it is still in practice. Medicinal plants are the backbone of Ayurveda, which heavily relies on the plant-derived therapeutics. While Ayurveda is becoming more popular in several countries throughout the World, lack of authent...

journal_title：BMC complementary and alternative medicine

authors： Vassou SL,Nithaniyal S,Raju B,Parani M

更新日期：2016-07-18 00:00:00

abstract：BACKGROUND:Acupuncture is not considered a conventional therapy for post-stroke sequelae but it might have some additional positive effects on early rehabilitation. We conducted this trial to determine whether acupuncture has additional effects in early comprehensive rehabilitation for acute ischemic stroke and dysfunc...

journal_title：BMC complementary and alternative medicine

authors： Chen L,Fang J,Ma R,Gu X,Chen L,Li J,Xu S

更新日期：2016-07-18 00:00:00

abstract：BACKGROUND:Primary insomnia is a widespread and refractory disease. Moxibustion therapy for insomnia shows some advantages compared with conventional therapies. This systematic review and meta-analysis of randomized controlled trials (RCTs) was conducted to evaluate the effectiveness and safety of moxibustion therapy f...

journal_title：BMC complementary and alternative medicine

authors： Sun YJ,Yuan JM,Yang ZM

更新日期：2016-07-13 00:00:00

abstract：BACKGROUND:For their analgesic and anti-arthritic effects, Aconitum species have been used in folk medicine in some East Asian countries. Although their analgesic effect is attributed to its action on voltage-dependent sodium channels, they also suppress purinergic receptor expression in dorsal root ganglion neurons in...

journal_title：BMC complementary and alternative medicine

authors： Yang J,Park KS,Yoon JJ,Bae HB,Yoon MH,Choi JI

更新日期：2016-07-13 00:00:00

abstract：BACKGROUND:Cornus officinalis, is a deciduous tree native to the eastern Asia, distributes mainly in (e.g. Korea, as well as China, and Japan). It is used as folk medicine to backache, polyuria, hypertension and nervous breakdown. Pharmacological studies have demonstrated that C. officinalis possess anti-oxidant, anti-...

journal_title：BMC complementary and alternative medicine

authors： Hwang KA,Hwang YJ,Song J

更新日期：2016-07-08 00:00:00

abstract：BACKGROUND:African trypanosomosis is the disease caused by extracellular protozoan parasites of the genus Trypanosoma transmitted by tsetse flies. The current study has evaluated the trypanocidal activity of Commiphora swynnertonii extracts on Trypanosoma congolense. METHODS:The effect of ethanolic stem bark and resin...

journal_title：BMC complementary and alternative medicine

authors： Nagagi YP,Silayo RS,Kweka EJ

更新日期：2016-07-08 00:00:00

abstract：BACKGROUND:Khaya grandifoliola (Meliaceae) and Entada africana (Fabaceae) are traditionally used in Bamun (a western tribe of Cameroon) traditional medicine for the treatment of liver related diseases. In this study, the synergistic hepatoprotective effect of respective active fractions of the plants were investigated ...

journal_title：BMC complementary and alternative medicine

authors： Njayou FN,Kouam AF,Simo BF,Tchana AN,Moundipa PF

更新日期：2016-07-07 00:00:00

abstract：BACKGROUND:To extract, purify, and identify the effective constituents of aqueous extract of Fructus Chebulae Immaturus, and analyze the bactericidal effects of total tannins. METHODS:Preparative thin layer chromatography and semi-preparative high performance liquid chromatography were used to isolate and purify the t...

journal_title：BMC complementary and alternative medicine

authors： Li K,Lin Y,Li B,Pan T,Wang F,Yuan R,Ji J,Diao Y,Wang S

更新日期：2016-07-02 00:00:00

abstract：BACKGROUND:Increased platelet aggregation is implicated in the pathogenesis of ischemic stroke and anti-platelet strategy may contribute to its therapy. Panaxatriol saponin (PTS), the main components extracted from Panax notoginseng, has been shown to be efficacious in the prevention and treatment of ischemic stroke in...

journal_title：BMC complementary and alternative medicine

authors： Qi H,Huang Y,Yang Y,Dou G,Wan F,Zhang W,Yang H,Wang L,Wu C,Li L

更新日期：2016-06-08 00:00:00

abstract：BACKGROUND:The ethanol extract of KOTMIN13, composed of Inula japonica Flowers, Trichosanthes kirilowii Semen, Peucedanum praeruptorum Radix, and Allium macrostemon Bulbs, was investigated for its anti-asthmatic and anti-allergic activities. METHODS:The anti-asthmatic effects of KOTMIN13 were evaluated on ovalbumin (O...

journal_title：BMC complementary and alternative medicine

authors： Lee E,Kim SG,Park NY,Park HH,Jeong KT,Choi J,Lee IH,Lee H,Kim KJ,Lee E

更新日期：2016-06-06 00:00:00

abstract：BACKGROUND:Mineral Pitch (MP) is a dark brown coloured humic matter originating from high altitude rocks. It is an Ayurvedic medicinal food, commonly used by the people of the Himalayan regions of Nepal and India for various body ailments. METHODS:The Huh-7 cells were treated with different concentrations of MP for 24...

journal_title：BMC complementary and alternative medicine

authors： Pant K,Gupta P,Damania P,Yadav AK,Gupta A,Ashraf A,Venugopal SK

更新日期：2016-05-27 00:00:00

abstract：BACKGROUND:Artemisia scoparia is traditionally used in the local system of medicine in kidney disorders. This study aimed at scrutinizing the nephroprotective prospective of A. scoparia methanol extract against carbon tetrachloride (CCl4) provoked DNA damages and oxidative stress in kidneys of rat. METHODS:Dried aeria...

journal_title：BMC complementary and alternative medicine

authors： Sajid M,Khan MR,Shah NA,Ullah S,Younis T,Majid M,Ahmad B,Nigussie D

更新日期：2016-05-27 00:00:00

abstract：BACKGROUND:Artemisia princeps Pamp (APP), Leonurus japonicas Houtt (LJH), and Gardenia jasminoides Ellis fruit (GJE) have been traditionally used in East Asia to treat women's diseases related to reproductive system. They may attenuate the deterioration of energy, lipid, glucose and bone metabolism by estrogen deficien...

journal_title：BMC complementary and alternative medicine

authors： Yang HJ,Kim MJ,Kwon DY,Moon BR,Kim AR,Kang S,Park S

更新日期：2016-05-23 00:00:00

abstract：BACKGROUND:Metabolic syndrome may lead to many complications, such as nonalcoholic fatty liver disease (NAFLD). A natural and effective therapeutic agent for patients with NAFLD is urgently needed. In a previous study, we showed that Rhodiola crenulata root extract (RCE) regulated hepatic gluconeogenesis through activa...

journal_title：BMC complementary and alternative medicine

authors： Lin KT,Hsu SW,Lai FY,Chang TC,Shi LS,Lee SY

更新日期：2016-05-17 00:00:00

abstract：BACKGROUND:Rhus verniciflua Stokes (RVS) belongs to the Anacardiaceae family and traditionally used for cancer treatment. RVS and butein, a major compound of RVS, were known to induce apoptosis via AKT inhibition in cancer cells. Thus, in this study, we investigated the effect of RVS and its derivative compounds (fiset...

journal_title：BMC complementary and alternative medicine

authors： Choi HS,Kim MK,Choi YK,Shin YC,Cho SG,Ko SG

更新日期：2016-04-27 00:00:00

abstract：BACKGROUND:Radiotherapy is of critical importance in the treatment of breast cancer. However, not all patients derive therapeutic benefit and some breast cancers are resistant to the treatment, and are thus evidenced with prospective distant metastatic spread and local recurrence. In this study, we investigated the pot...

journal_title：BMC complementary and alternative medicine

authors： Yan Y,Li Z,Xu X,Chen C,Wei W,Fan M,Chen X,Li JJ,Wang Y,Huang J

更新日期：2016-03-31 00:00:00

abstract：BACKGROUND:Type 2 diabetes is a serious problem for developed and developing countries. Prevention of prediabetes progression to type 2 diabetes with the use of natural products appears to be a cost-effective solution. Zingiber mioga has been used as a traditional food in Asia. Recent research has reported the potentia...

journal_title：BMC complementary and alternative medicine

authors： Jo SH,Cho CY,Lee JY,Ha KS,Kwon YI,Apostolidis E

更新日期：2016-03-31 00:00:00

abstract：BACKGROUND:Danqi pill (DQP) is one of the most widely prescribed formulas and has been shown to have remarkable protective effect on coronary heart disease (CHD). However, its regulatory effects on lipid metabolism disorders haven't been comprehensively studied so far. We aimed to explore the effects of DQP on Peroxiso...

journal_title：BMC complementary and alternative medicine

authors： Chang H,Wang Q,Shi T,Huo K,Li C,Zhang Q,Wang G,Wang Y,Tang B,Wang W,Wang Y

更新日期：2016-03-22 00:00:00

abstract：BACKGROUND:Tai Chi Chuan (TCC) is known to be a good calisthenics for people. This study examined the relationship between pulse harmonics and autonomic nervous modulation in TCC practitioners. METHODS:Power spectral measures of right pulse wave and heart rate variability (HRV) measures were compared between TCC pract...

journal_title：BMC complementary and alternative medicine

authors： Lu WA,Chen YS,Kuo CD

更新日期：2016-02-29 00:00:00

abstract：BACKGROUND:Type 2 diabetes mellitus is a major health threat worldwide. Cosmos caudatus is one of the medicinal plants used to treat type 2 diabetes. Therefore, this study aims to determine the effectiveness and safety of C. caudatus in patients with type 2 diabetes. Metabolomic approach will be carried out to compare ...

journal_title：BMC complementary and alternative medicine

authors： Cheng SH,Ismail A,Anthony J,Ng OC,Hamid AA,Yusof BN

更新日期：2016-02-27 00:00:00

abstract：BACKGROUND:Anoectochilus formosanus has been used as a Chinese folk medicine and is known as the "King of medicine" in Chinese society due to its versatile pharmacological effects such as anti-hypertension, anti-diabetes, anti-heart disease, anti-lung and liver diseases, anti-nephritis and anti-Rheumatoid arthritis. Ki...

journal_title：BMC complementary and alternative medicine

authors： Hsiao HB,Hsieh CC,Wu JB,Lin H,Lin WC

更新日期：2016-02-25 00:00:00

abstract：BACKGROUND:Fibrosis is a major contributor to systemic sclerosis (SSc)-related morbidity, and rapid, progressive skin involvement predicts later mortality. Western medicine therapies for SSc cannot produce satisfactory effects currently, while Traditional Chinese Medicine (TCM), such as the Wenyang Huazhuo Tongluo (WYH...

journal_title：BMC complementary and alternative medicine

authors： Han L,Bian H,Ouyang J,Bi Y,Yang L,Ye S

更新日期：2016-02-20 00:00:00

abstract：BACKGROUND:Of patients undergoing surgery, 22 to 57% have been reported to be using naturopathic medicines. Several of these medicines have been reported to increase bleeding or enhance the effect of other drugs that increase bleeding. The Swedish Medical Products Agency recommends cessation of the use of the naturopat...

journal_title：BMC complementary and alternative medicine

authors： Bagge A,Schött U,Kander T

更新日期：2016-02-17 00:00:00

abstract：BACKGROUND:Gualou Xiebai Decoction (GXD) is a well-known traditional Chinese recipe. It has been used to treat cardiovascular disorders for nearly two thousand years. But there is a lack of reports on cardiac fibrosis and underlying mechanism. METHODS:Myocardial infarction was performed by ligation of left anterior de...

journal_title：BMC complementary and alternative medicine

authors： Ding YF,Peng YR,Shen H,Shu L,Wei YJ

更新日期：2016-02-04 00:00:00

abstract：BACKGROUND:Traditionally, Pine has been used to treat oxidative and inflammatory disorders. The study was aimed to investigate biological potential of phytoconstituents of Pinus plant species: Pinus roxburghii, Pinus wallichiana and Pinus gerardiana using in-vitro antioxidant, anti-inflammatory and antimicrobial method...

journal_title：BMC complementary and alternative medicine

authors： Sharma A,Goyal R,Sharma L

更新日期：2016-01-28 00:00:00